EDG2 (LPAR1, EDG-2, EDG2, Gpcr26, Rec.1.3, Vzg-1, Ventricular Zone Gene 1, LPA Receptor 1, LPA-1, LPA1, Mrec1.3, VZG1)

Size

£709.00

SKU:: 170415
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 15aa from the N-terminus of human EDG2. Species sequence homology: bat, bovine, chicken, canine, hamster, equine, mouse, porcine, rabbit, rat and sheep.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: EDG2, a Lysophospholipid/Lysosphingolipid Receptor, mediates growth factor-like activities such as proliferation, platelet aggregation, and chemotaxis. EDG2 is involved in myelin formation or maintenance. It is activated by platelet-derived lysophosphatidic acid (LPA), a lipid metabolite present in serum that acts ubiquitously. Although alternate translation start codons and polyadenylation sites have been reported, the alternative splicing transcripts each encode identical proteins. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.