Dopamine D2 Receptor (DRD2, D2 Dopamine Receptor, D2R, Dopamine Receptor D2 isoform, Dopamine 2 Receptor, D(2) Dopamine Receptor, D2DR, Dopamine Receptor D2)

Size

£709.00

SKU:: 170387
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human Dopamine D2 Receptor. Species sequence homology: gibbon, monkey and porcine.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.