Dopamine D2 Receptor (DRD2, D2 Dopamine Receptor, D2R, Dopamine Receptor D2 Isoform, Dopamine 2 Receptor, D(2) Dopamine Receptor, D2DR, Dopamine D2 Receptor, Dopamine Receptor D2)

Size

£787.00

SKU:: 170386
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 19aa from 3rd cytoplasmic domain of human DRD2. Species Sequence Homology: chimpanzee, gorilla and marmoset, 100%; gibbon, monkey and rabbit, 95%; canine, bovine, panda, equine and porcine, 89%; mouse, rat, ferret, bat, hamster and elephant, 84%.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. Applications: Suitable for use in Immunohistochemistry. Other applications have not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 5-10ug/ml. Requires HIER using sodium citrate buffer pH6.0 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.