CHRM3 (CHRM3, M3, Muscarinic Receptor M3, Muscarinic M3 Receptor, EGBRS, HM3, M3 Muscarinic Receptor)

Size

£646.00

SKU:: 170309
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 19aa from the C-terminus of human CHRM3. Species Sequence Homology: bovine, chimpanzee, canine, guinea pig, hamster, equine, mouse, porcine, rabbit, rat and sheep.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Muscarinic Acetylcholine Receptor 3 (CHRM3) is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of CHRM3 causes secretion in glandular tissues. Mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 72ug/ml using heat induced antigen retrieval in citrate buffer., pH 6.0 is recommended. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.