CDC7 (Kinase Domain) (Cdc7 Kinase, CDC7-like 1, CDC7L1, HsCDC7, HuCDC7, CDC7-related Kinase, Hsk1, MuCdc7)

Size

£735.00

SKU:: 170283
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 19aa from human CDC7. Species sequence homology: hamster, monkey, mouse and rat.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 6.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.