5HT1B Receptor (HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1b Receptor, 5-HT1DB, 5HT1B Receptor, HTR1DB, Serotonin 5-HT-1b Receptor, Serotonin Receptor 1B, Serotonin 1b Receptor, HTR1D2, Serotonin 1D beta Receptor)

Size

£735.00

SKU:: 170108
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human HTR1B/5HT1B. Species sequence homology: monkey and equine.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: 5-HT1B (5-HT1D beta), a Serotonin Receptor, inhibits neurotransmitter release from neuronal terminals. Knockout mutant mice lacking this receptor exhibit decreased anxiety, increased aggression, and augmented alcohol and cocaine consumption compared to controls. 5-HT1B receptors have been found to control areas of the human brain involved in migraine pain, bipolar disorder, and obsessive compulsive disorder. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 7ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.