169587
Tumor Necrosis Factor alpha (TNFa, TNF-alpha)
Size
£469.00
- SKU:
- 169587
- Purity:
- Purified.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human TNF-a.
- Clone:
- 13F230
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with sterile H20.
- Extra Details:
- Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism and coagulation. TNF’s primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases, autoimmune diseases, insulin resistance and cancer. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Intracellular Staining. Other applications not tested. Recommended Dilution: ELISA: 1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice