Periplaneta Americana Igloo L 1-75 (Pam-Igloo-L) (Not for Export EU)

Size

£453.00

SKU:: 169567
Purity:: Serum.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Peptide corresponding to Pam-Igloo-L.
Format:: Supplied as a liquid in 50% glycerol.
Extra Details:: Axogenesis and synaptic signal transmission in the vertebrate nervous system are based on the abundant expression of the growth-associated protein GAP-43. In non-vertebrates a GAP-43 related gene (igloo, invertebrate GAP-43 like) was found in Drosophila and encodes two proteins, IGLOO-L and IGLOO-S, with sequence homology and similar biochemical activity to GAP-43. As for Drosophila, we found two putative pigl mRNAs, pigl-L and pigl-S, in the cockroach (Fig. 1). Immunocytochemical investigations with a antiserum to Pam-Igl L and Pam- Igl S provide a function for Pam-Igloo L in establishment or maintenance of synaptic contacts and can help to understand the ongoing expression of GAP-43 in the mature nervous system (Hänold,2004). Applications: Suitable for use in ELISA and Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.