169542
Interleukin 10 (IL-10)
Size
£513.00
- SKU:
- 169542
- Purity:
- Purified.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to mouse IL-10.
- Clone:
- 13F218
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with 500ul sterile ddH2O.
- Extra Details:
- IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotrophic effects in immunoregulation and in- flammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B-cell survival, proliferation, and antibody production. This cytokine can block NF-kB activity, and is involved in the regulation of the JAK-STAT signalling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Applications: Suitable for use in Direct ELISA, Western Blot, Immunoprecipitation and Intracellular Staining. Other applications not tested. Recommended Dilution: Direct ELISA: 1:5000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice