Factor XI

Size

£704.00

SKU:: 169031
Application:: IP
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Plasma FXI
Format:: Supplied as a lyophilized powder. No preservative added. Reconstitute with 1ml sterile dH2O.
Extra Details:: Factor XI is a glycoprotein (MW 160,000) composed of two identical polypeptide chains. In electrophoresis it migrates in the gamma region. It is stable on storage, heat\stable at 56ºC for 30 minutes and not adsorbed by gels. Factor XI also occurs in platelets (MW 52,000). Factor XI is converted to an active enzyme by FXIIa but can be activated by other proteases such as trypsin. FXIa activates FIX, but can also activate FXII and plasminogen. Platelet membrane FXI can substitute for plasma FXI in coagulation. Applications: Suitable for use in Immunoprecipitation, Immunoelectrophoresis, Bi-dimensional Electrophoresis and Radial Immunodiffusion. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.