168718-AF
CD71 (Transferrin Receptor, Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR) (BSA & Azide Free)
Size
£646.00
- SKU:
- 168718-AF
- Purity:
- Purified by Protein A/G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Human thymocytes (T-cells). Cellular Localization: Secreted, cell surface, cell membrane, melanosome
- Clone:
- 66IG10
- Format:
- Supplied as a liquid inPBS. Also available with BSA and azide, see 168718.
- Extra Details:
- It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Applications: Suitable for use in Immunofluorescence, ELISA and Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1-2ug/million cells Immunofluorescence: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: CCRF-CEM, Jurkat or K-562 cells. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice