Paprotrain ((Z) a-(3-Pyridinylmethylene)-1H-indo le-3-acetonitrile)

Size

£293.00

SKU:: 167689
Molecular Weight:: 245.28
Purity:: ~99%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 57046-73-8
Format:: Supplied as a yellow solid.
Extra Details:: Solubility: 100mM in DMSO and 10mM in ethanol Molecular Weight: ~245.28 Biological Activity: Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (Ki = 3.4um). Inhibits the basal ATPase activity of MKLP-2 (IC50 = 1.35um). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.