DBZ (N-[(1S)-2-[[(7S)-6,7-Dihydro-5-meth yl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl -2-oxoethyl]-3,5-difluorobenzeneacetamide)

Size

£643.00

SKU:: 167642
Molecular Weight:: 463.48
Purity:: ~98%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 209984-56-5
Format:: Supplied as an off-white solid.
Extra Details:: Solubility: 100mM in DMSO Molecular Weight: ~463.48 Biological Activity: Inhibitor of y-secretase. Blocks Notch cleavage (IC50< 2nm) in a cell-based assay; inhibits the Notch pathway. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.