GluA1/GluR1 Glutamate Receptor (GluA1, Glr-1, Glur-1, HIPA, Glur1, GluR-A, AI853806, 2900051M01Rik, GluRA, Glr1, MGC13325, GLUH1, GluA1, GLUR1, HBGR1, GLURA, gluR-, GluA1)

Size

£626.00

SKU:: 167589
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Fusion protein corresponding to aa1-389 (extracellular N-terminus) of rat GluA1/GluR1.
Clone:: S355-1
Format:: Supplied as a liquid in PBS pH7.4, 50% glycerol, 0.09% sodium azide.
Extra Details:: Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3). Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 1ug/ml was sufficient for detection of GluA1/GluR1 in 20ug of mouse brain membrane lysate and assayed by Western Blot using IgG (HRP)goat anti-mouse as the secondary antibody. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice