ASIC1 (Acid-sensing (proton-gated) ion channel)

Size

£626.00

SKU:: 167577
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Fusion protein corresponding to aa460-526 from the cytoplasmic C-terminus of mouse ASIC1. Cellular Localization: Cell membrane
Clone:: S271-44
Format:: Supplied as a liquid in PBS pH 7.4, 0.09% sodium azide, 50% glycerol.
Extra Details:: Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry, andImmunofluorescence. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap