trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene

Size

£460.00

SKU:: 166866
Molecular Weight:: 286.32
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 57404-88-3
Format:: Supplied as a Brown Solid
Extra Details:: trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen. Melting Point: >158°C (dec.) Solubility: DMSO, Methanol, THF