LY 364947

Size

£397.00

SKU:: 164789
Molecular Weight:: 272.3
Storage Conditions:: RT/4°C
Supplier:: United States Biological
CAS Number:: 396129-53-6
Format:: Very Dark Brown Solid
Extra Details:: Selective inhibitor of TGF-β type-I receptor (TGF-β RI, TGFR-I, TβR-I, ALK-5) (IC50 values are 59, 400 and 1400nM for TGR-β RI, TGF-β RII and MLK-7K respectively). Inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC50 values are 47 and 89nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay. CAS Number: 396129-53-6 Molecular Formula: C₁₇H₁₂N₄ Molecular Weight:: 272.3 Appearance: Very Dark Brown Solid Solubility: DMSO (Slightly, Heated) Storage: Refrigerator