163934
DL-Methotrexate Dipotassium Salt Dihydrate
Size
£581.00
- SKU:
- 163934
- Molecular Weight:
- 566.65
- Purity:
- As reported
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- Free acid: 60388-53-6
- Format:
- Yellow to light orange powder
- Extra Details:
- DL-Methotrexate is a folic acid antagonist and potent anticancer agent. Amethopterin blocks DNA synthesis by preventing the production of tetrahydrofolate cofactors which are required to make thymidine. Amethopterin is actively transported into cells by the folate transporter where it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, a dihydrofolate reductase inhibitor. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic Acid Dipotassium Salt Dihydrate; DL-AmethopterinvDipotassium Salt Dihydrate; NSC 117356 Dipotassium Salt Dihydrate CAS No: Free acid: 60388-53-6 Molecular Formula: C₂₀H₂₄K₂N₈O₇ Molecular Weight: 566.65 Appearance: Yellow to light orange powder Purity: As reported Melting Point: xxx°C Solubility: Add a minimal amount of 0.1N NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1 week refrigerated and for 1 month frozen at -20 °C Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient