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160703

3-Oxo-7α-hydroxy-5β-cholanoic Acid

Size

£558.00

SKU:
160703
Molecular Weight:
390.56
Purity:
≥99%
Storage Conditions:
4°C
Supplier:
United States Biological
CAS Number:
4185-00-6
Format:
White to pale yellow solid
Extra Details:
3-Oxo-7α-hydroxy-5β-cholanoic acid is a fatty acid that is an intermediate in the synthesis of bile acids. It is formed by the addition of hydroxyl groups to 7α, 12β-dihydroxycholesterol. The ethyl esters of 3-oxo-7α, 12β-dihydroxycholesterol are converted to 3-oxo-7α, 12β, 15β-, and 16β hydroxycholesterols by the action of bacteria such as Clostridium sp. or Propionibacterium sp. The formation of 3-oxo-7α, 12β, 15β-, and 16β hydroxycholesterols may be promoted by the presence of hydrochloric acid (HCl) or trifluoroacetic acid (TFA). 3OHDCA can be used for profiling human liver microsomes via HPLC analysis. Synonyms: (5β,7α)-7-Hydroxy-3-oxo-cholan-24-oic Acid; 7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 7α-Hydroxy-3-oxo-5β-cholanic Acid; 7α-Hydroxy-3-keto-5β-cholanoic Acid; 7α-Hydroxy-3-oxo-5β-chol-24-oic Acid; 7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 7α-Hydroxy-3-oxo-5β-cholanic Acid; 7α-Hydroxy-3-oxo-5β-cholanoic Acid; 3-Oxo-7α-hydroxy-5β-cholanic Acid; 3-Oxo-7α-hydroxy-5β-cholanoic Acid; 3-Oxo-7α-hydroxycholan-24-oic Acid; 3-Oxodeoxycholic Acid CAS No: 4185-00-6 Molecular Formula: C₂₄H₃₈O₄ Molecular Weight: 390.56 Appearance: White to pale yellow solid Purity: ≥99% Melting Point: 109-113°C Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Shipping Conditions:
Ambient