IP-10, Recombinant, Rat (Cxcl10, C-X-C Motif Chemokine 10, 10kD Interferon gamma-induced Protein, Gamma-IP10, Interferon-inducible Protein 10, Protein Mob-1, Small-inducible Cytokine B10, Inp10, Mob1, Scyb10)

Size

£341.00

SKU:: 149691
Purity:: ~98% (SDS-PAGE and HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder.
Extra Details:: IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6kD protein consisting of 77aa including the four conserved cysteine residues present in CXC chemokines. Source: Recombinant protein corresponding to rat IP-10, expressed in E.coli. Biological Activity: Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10-50ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.