Pf4, Recombinant, Mouse (Platelet Factor 4, PF-4, C-X-C Motif Chemokine 4, Cxcl4, Scyb4)

Size

£364.00

SKU:: 149683
Molecular Weight:: 8.2
Purity:: ≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (1EU/ug)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder. Reconstitute with sterile ddH2O to 0.1-1mg/ml.
Extra Details:: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2kD protein containing 76aa, including the four highly conserved residues present in CXC chemokines. Recombinant protein corresponding to mouse PF-4, expressed in E. coli Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml. Amino Acid Sequence: VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.