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149679

CCL19, Recombinant, Mouse (MIP-3beta)

Size

£364.00

SKU:
149679
Molecular Weight:
9.2
Purity:
≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (<1EU/ug)
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Supplied as a lyophilized powder. Reconsitute in sterile ddH2O, 0.1% HSA or BSA to 0.1-1mg/ml. Do not vortex.
Extra Details:
MIP-3beta is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3beta is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3beta is active on murine cells. Recombinant Murine MIP-3beta is a 9.2kD protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Recombinant protein corresponding to mouse MIP-3 beta, expressed in E.coli. Accession Number: NP_036018.1 Biological Activity: Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90ng/ml. Amino Acid Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O, 0.1% HSA or BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice