MCP-1, Recombinant, Mouse (C-C Motif Chemokine 2, Monocyte Chemoattractant Protein 1, Monocyte Chemotactic Protein 1, MCP-1, Platelet-derived Growth Factor-inducible Protein JE, Small-inducible Cytokine A2, Ccl2, Je, Mcp1, Scya2)

Size

£351.00

SKU:: 149671
Purity:: ~98% (SDS-PAGE and HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder.
Extra Details:: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8kD protein containing 125aa including the four highly conserved cysteine residues present in the CC chemokines. Source: Recombinant protein corresponding to mouse MCP-1, expressed in E.coli. Biological Activity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1-20ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.