FBXL16 (C16orf22, FBL16, F-box/LRR-repeat Protein 16, F-box and Leucine-rich Repeat Protein 16, FLJ33735, MGC33974)

Size

£655.00

SKU:: 146795
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 18aa from near the C-terminus of human FBXL16.
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40aa F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Spleen Tissue Lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.