SMANT hydrochloride (N-(4-Bromophenyl)-3,5-dimethyl-1-pi peridinepropanamide hydrochloride)

Size

£382.00

SKU:: 145693
Molecular Weight:: 375.73
Purity:: ~99% (HPLC)
Storage Conditions:: RT
Supplier:: United States Biological
CAS Number:: 1177600-74-6
Format:: Supplied as a off-white solid.
Extra Details:: Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC50 = 1.1um). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy. Formula: C16H23BrN2O.HCl Solubility: DMSO (~100mM), H2O (~20mM), Ethanol (~20mM) Molecular Weight: ~375.73 Storage and Stability: Store at RT. Stable for 12 months.