S-Duloxetine Hydrochloride (Potent 5-HT and NA Reuptake Inhibitor, Blocks Dopamine Reuptake, (+)-S-N-Methyl-3-(1-naphthyloxy)- 3-(2-thienyl)propanamine hydrochloride)

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£267.00

SKU:: 145691
Molecular Weight:: 333.88
Purity:: ≥99% (HPLC)
Storage Conditions:: RT
Supplier:: United States Biological
CAS Number:: 136434-34-9
Format:: Supplied as a off-white solid.
Extra Details:: High affinity, competitive 5-HT and norepinephrine (NE) re-uptake inhibitor (Ki values are 8.5 and 45nm for 5-HT and NE reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46nm for 5-HT and NE reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki=300nm in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable. CAS Number: 136434-34-9 Formula: C18H19NOS.HCl Solubility: DMSO (~100mM), H2O (~10mM) with gentle warming Molecular Weight: ~333.88 Storage and Stability: Store at RT. Stable for 12 months.