145673
Entacapone ((2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide)
Size
£267.00
- SKU:
- 145673
- Molecular Weight:
- 305.29
- Purity:
- ~99% (HPLC)
- Storage Conditions:
- RT
- Supplier:
- United States Biological
- CAS Number:
- 130929-57-6
- Format:
- Supplied as a yellow solid.
- Extra Details:
- Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3nm for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits alpha-synuclein aggregation in an in vitro assay; blocks alpha-synuclein-induced cell death in PC-12 cells. Formula: C14H15N3O5 Solubility: DMSO (~100mM), Ethanol (~10mM) Molecular Weight: ~305.29 Storage and Stability: Store at RT. Stable for 12 months.
- Shipping Conditions:
- Blue Ice