145663
BMS 303141 (ATP Citrate Lyase Inhibitor, Orally Bioavailable, 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide)
Size
£539.00
- SKU:
- 145663
- Molecular Weight:
- 424.3
- Purity:
- ~99% (HPLC)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 943962-47-8
- Format:
- Supplied as a white crystalline solid.
- Extra Details:
- ATP citrate lyase (ACL) inhibitor (IC50 = 0.13um for human recombinant ACL); blocks lipid synthesis (IC50 = 8um in HepG2 cells). Displays no cytotoxicity up to a concentration of 50um. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable. Sequence: C19H15Cl2NO4S Solubility: DMSO (~10mM), Ethanol (~50mM) Molecular Weight: ~424.3 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice