8-pCPT-2-O-Me-cAMP-AM (007-AM) (8-(4-Chlorophenylthio)-2'-O-methylad enosine-3',5'-cyclic monophosphate acetoxymethyl ester)

Size

£558.00

SKU:: 145660
Molecular Weight:: 557.9
Purity:: ≥97% (HPLC)
Storage Conditions:: -70°C
Supplier:: United States Biological
CAS Number:: 1152197-23-3
Format:: Supplied as a white lyophilized solid.
Extra Details:: Selective Epac activator; cAMP analog. Induces Rap activation and junction tightening in HUVECs; triggers adhesion of Jurkat-Epac1 cells to fibronectin. This product is a mixture of axial and equatorial isomers. Both isomers give 8CPT-2Me-cAMP after esterase cleavage. Sequence: C20H21ClN5O8PS Solubility: DMSO (~100mM) Molecular Weight: ~557.9 Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.