MATN1 (Matrilin-1, CMP, CRTM)

Size

£812.00

SKU:: 145518
Purity:: Purified by Protein A or G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa23-496 from human Matrilin-1, CHO-derived (UniProt # P21941).
Clone:: 828806
Format:: Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.
Extra Details:: Matrilin1, also known as Cartilage Matrix Protein (CMP) is a 5060kD extracellular matrix protein that belongs to the superfamily of von Willebrand factor A (VWA) containing proteins. It is primarily expressed in cartilage and functions as a bridging component between proteins of the collagenous matrix. Mature human Matrilin1 contains two VWA domains that flank one EGFlike repeat, followed by a Cterminal coiled coil domain. The Matrilins differ in the number of VWA domains (one or two) and EGFlike repeats (one, three, four, or ten) they contain. Human Matrilin1 shares 91% aa sequence identity with human and rat Matrilin1. The coiled coil domain of Matrilin1 mediates disulfidelinked homotrimer formation. It can also assemble into heterooligomers with Matrilin2, 3, and 4. Applications: Suitable for use in ELISA and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunocytochemistry: 825ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice