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145287-PE

TNF alpha (Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2) (PE)

Size

£843.00

SKU:
145287-PE
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
4°C Do Not Freeze
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
E. coli-derived mouse TNF alpha recombinant protein (Position: L80-L235).
Format:
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Extra Details:
TNFα(Tumor Necrosis Factor alpha) gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. UniProt Number: P06804 Gene ID: TNF Applications: Suitable for use in FLISA, Western Blot, Immunohistochemistry (Paraffin), Neutralization and Immunoprecipitation. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice