TIMP2 (CSC-21K, Tissue inhibitor of metalloproteinases 2)

Size

£620.00

SKU:: 145278
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: A synthetic peptide corresponding to a sequence at the C-terminal of human TIMP-2(205-220aa RGAAPPKQEFLDIEDP), identical to the related rat and mouse sequences.
Format:: Supplied as a liquid. Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Extra Details:: TIMP2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. UniProt Number: P16035 Gene ID: TIMP2 Applications: Suitable for use in Western Blot and Immunohistochemistry (Paraffin). Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.