Talin (TLN, KIAA1027, ILWEQ, TALIN)

Size

£620.00

SKU:: 145246
Application:: WB
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified chicken gizzard talin.
Clone:: Tal-33
Format:: Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Extra Details:: Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p. UniProt Number: Human(Q9Y490), Mouse(P26039), Rat(Q498D4); Human(Q9Y4G6), Mouse(Q71LX4), Rat(D3ZA84) Gene ID: TLN1; TLN2 Applications: Suitable for use in Western Blot. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.