144690
HSP25 (HSP27, HSP28, CMT2F, HMN2B, 28kD heat shock protein, Estrogen-regulated 24kD protein, Heat shock 27kD protein)
Size
£620.00
- SKU:
- 144690
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Partially purified inhibitor of actin polymerization (IAP) protein from turkey gizzard smooth muscle.
- Clone:
- SJ-25
- Format:
- Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
- Extra Details:
- The heat-shock proteins (HSPs) belong to a larger group of polypeptides, the stress proteins, that are induced in various combinations in response to environmental challenges and developmental transitions. Heat-shock 27-kD protein1also knows as HSPB. Synthesis of the small (27-kD) HSP has been shown to be correlated with the acquisition of thermotolerance. HSP27 gene is mapped to 7q11.23. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. UniProt Number: Human(P04792), Mouse(P14602), Rat(P42930) Gene ID: HSPB1 Applications: Suitable for use in Western Blot, Immunohistochemistry (Paraffin and Frozen), and Immunocytochemistry. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice