144561
GAP43 (Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46)
Size
£620.00
- SKU:
- 144561
- Purity:
- Purified by immunoaffinity chromatography
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminal of the human GAP-43, different from the related mouse and rat sequences by one amino acid.
- Format:
- Supplied as a lyophilized powder from PBS. Each vial contains 5% BSA, 0.05% thimerosal, 0.05%g sodium azide. Reconstitute with 200ul sterile ddH2O.
- Extra Details:
- Growth Associated Protein-43(GAP-43), also known as nerve growth-related growth peptide GAP43, shares a high degree of homology between the sequence of the human gene and the rat gene. GAP-43 is considered a crucial component of an effective regenerative response in the nervous system. Somatic cell hybrids demonstrate localization of the GAP-43 gene to human chromosome 3 and to mouse chromosome 16. GAP-43 has been termed a "growth" or "plasticity" protein because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. GAP-43 regulates growth of axons and modulates the formation of new connections. UniProt Number: P17677 Gene ID: GAP43 Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: paraffin Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice