144434
Cytokeratin Peptide 18 (K18, Keratin-18, CK-18, Cytokeratin-18, CYK18, Cell proliferation-inducing gene 46 protein)
Size
£620.00
- SKU:
- 144434
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.
- Clone:
- CK-18
- Format:
- Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
- Extra Details:
- Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis. UniProt Number: Human(P05783), Mouse(P05784), Rat(Q5BJY9) Gene ID: KRT18 Applications: Suitable for use in Western Blot, Immunohistochemistry (Paraffin and Frozen). Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term. Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice