RELM beta, Recombinant, Mouse (Resistin-like beta, Cysteine-rich Secreted Protein A12-beta, Cysteine-rich Secreted Protein FIZZ2, RELMbeta, Fizz2)

Size

£364.00

SKU:: 143480
Molecular Weight:: 18
Purity:: ≥98% (SDS-PAGE gel and HPLC analyses). Endotoxin: <0.1ng/ug of protein (<1EU/ug).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder from 10mM acetic acid. Reconstitute with sterile ddH2O to 0.1-1mg/ml. Do not vortex. For extended storage, dilute in a buffer containing a carrier protein (example 0.1% BSA)
Extra Details:: RELMβ (Resistin-like molecule β/FIZZ2) is a disulfide-linked, homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known, but it has been suggested that it plays a regulatory role during inflammation, and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokines, resistin and RELMα. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant mouse RELMβ is an 18kD protein, consisting of two identical 83 amino acid polypeptide chains linked by a single disulfide bond. Amino Acid Sequence: MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice