RAD9A (Cell cycle checkpoint control protein, DNA repair exonuclease rad9 homolog A, hRAD 9, hRAD9, Rad 9, RAD 9A, RAD9 (S pombe) homolog, RAD9 homolog A, RAD9 homolog, RAD9A)

Size

£722.00

SKU:: 143240
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant human Rad9A protein fragments expressed in E. coli
Clone:: 13k113
Format:: Supplied as a liquid in PBS, pH 7.4, 0.2% sodium azide, 50% glycerol.
Extra Details:: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3´ to 5´ exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.