IL18 binding protein (IL-18BP, IL18 BP, IL18 BPa, IL18BP, IL18BPa, Interleukin 18 binding protein, Interleukin-18-binding protein, MC51L 53L 54L homolog gene product, Tadekinig alfa, Tadekinig-alfa)

Size

£722.00

SKU:: 143200
Application:: WB
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant human IL18BP protein fragments expressed in E. coli.
Clone:: 13k73
Format:: Supplied as a liquid in ascites fluid.
Extra Details:: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn´s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:400 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.