TIAF1, Recombinant, Human, aa1-115, His-Tag (TGFB1-induced Anti-apoptotic Factor 1, MAJN, SPR210)

Size

£607.00

SKU:: 138758
Molecular Weight:: 16.6
Purity:: ~85% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.
Extra Details:: TGFB1-induced anti-apoptotic factor 1, also known as TIAF1, inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. This protein involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. Source: Recombinant protein corresponding to aa1-115 from human TIAF1 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~16.6kD (152aa) AA Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSH CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG MSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.