MBL2, Recombinant, Human, aa108-248, His-Tag (Mannose-binding Protein C, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1)

Size

£512.00

SKU:: 138694
Molecular Weight:: 18
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 2M urea, 0.2M sodium chloride, 20% glycerol.
Extra Details:: Mannose-binding protein C, also known as MBL2, is a member of the collectin family of patternrecognition molecules. MBL2 is a secreted glycoprotein that is synthesized as a 248aa precursor. The Protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. Source: Recombinant protein corresponding to aa108-248 from human MBL2 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~18kD (164aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSAASERKA LQTEMARIKK WLTFSLGKQV GNKFFLTNGE IMTFEKVKAL CVKFQASVAT PRNAAENGAI QNLIKEEAFL GITDEKTEGQ FVDLTGNRLT YTNWNEGEPN NAGSDEDCVL LLKNGQWNDV PCSTSHLAVC EFPI Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.