KIN17, Recombinant, Human, aa1-393, His-Tag (DNA/RNA-binding Protein KIN17, BTCD, KIN17, KIN)

Size

£512.00

SKU:: 138676
Molecular Weight:: 47.8
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.2M sodium chloride, 20% glycerol.
Extra Details:: DNA/RNA-binding protein KIN17, also known as KIN17, is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. KIN17 is ubiqutiously expressed with the highest levels of expression in muscle, heart and testis. SV40-transformed fibroblasts overexpress KIN17, which interacts with Large T antigen and reduces T-antigen-dependent DNA replication. Source: Recombinant protein corresponding to aa1-393 from human KIN17 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~47.8kD (416aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGKSDFL TPKAIANRIK SKGLQKLRWY CQMCQKQCRD ENGFKCHCMS ESHQRQLLLA SENPQQFMDY FSEEFRNDFL ELLRRRFGTK RVHNNIVYNE YISHREHIHM NATQWETLTD FTKWLGREGL CKVDETPKGW YIQYIDRDPE TIRRQLELEK KKKQDLDDEE KTAKFIEEQV RRGLEGKEQE VPTFTELSRE NDEEKVTFNL SKGACSSSGA TSSKSSTLGP SALKTIGSSA SVKRKESSQS STQSKEKKKK KSALDEIMEI EEEKKRTART DYWLQPEIIV KIITKKLGEK YHKKKAIVKE VIDKYTAVVK MIDSGDKLKL DQTHLETVIP APGKRILVLN GGYRGNEGTL ESINEKTFSA TIVIETGPLK GRRVEGIQYE DISKLA Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice