GGPS1, Recombinant, Human, His-Tag (Geranylgeranyl Pyrophosphate Synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl Diphosphate Synthase, Dimethylallyltranstransferase, Farnesyl Diphosphate Synthase, Farnesyltranstransferase, Geranylgeranyl Diphosphate Synthase, Geranyltranstransferase)

Size

£607.00

SKU:: 137989
Molecular Weight:: 37
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 10% glycerol.
Extra Details:: Geranylgeranyl pyrophosphate synthase isoform A, also known as GGPS1, is a member of the prenyltransferase family. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate, a precursor of geranylgeranylated proteins and carotenoids. GGPS1 is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Source: Recombinant protein corresponding to aa1-300 of human GGPS1, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~37kD Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MGSSHHHHHH SSGLVPRGSH MEKTQETVQR ILLEPYKYLL QLPGKQVRTK LSQAFNHWLK VPEDKLQIII EVTEMLHNAS LLIDDIEDNS KLRRGFPVAH SIYGIPSVIN SANYVYFLGL EKVLTLDHPD AVKLFTRQLL ELHQGQGLDI YWRDNYTCPT EEEYKAMVLQ KTGGLFGLAV GLMQLFSDYK EDLKPLLNTL GLFFQIRDDY ANLHSKEYSE NKSFCEDLTE GKFSFPTIHA IWSRPESTQV QNILRQRTEN IDIKKYCVHY LEDVGSFEYT RNTLKELEAK AYKQIDARGG NPELVALVKH LSKMFKEENE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice