HDAC10, Active, Recombinant, Human, FLAG-Tag (Histone Deacetylase 10, HD10)

Size

£983.00

SKU:: 137277
Molecular Weight:: 67
Purity:: Purified (~50%)
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 45mM Tris-HCl, pH 8.0, 124mM sodium chloride, 2.4mM potassium chloride, 0.05% Tween 20, 10% glycerol.
Extra Details:: HDAC10 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Source: Recombinant corresponding to aa2-631 from human HDAC10, fused to Flag-tag at N-terminal, expressed in Sf9 cells via a baculovirus expression system. Molecular Weight: ~67kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Specific Activity: ~3.6pmol/min/ug Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.