SYT13, Recombinant, Human, aa30-426, His-Tag (Synaptotagmin-13 Isoform 1, Synaptotagmin XIII)

Size

£544.00

SKU:: 137222
Molecular Weight:: 46.5
Purity:: ~85% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 30% glycerol, 1mM DTT, 1mM EDTA.
Extra Details:: SYT13 is a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. Source: Recombinant protein corresponding to human SYT13, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~46.5kD (420aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSCRHMHPK KGLLPRDQDP DLEKAKPSLL GSAQQFNVKK YADYSLRSTE EPTAPASPQP PNDSRLKRQV TEELFILPQN GVVEDVCVME TWNPEKAASW HDGGCDCYVQ GSVANRTGSV EAQTALKKRQ LHTTWEEGLV LPLAEEELPT ATLTLTLRTC LKTSAKEPSA GAGEVLLSIS YLPAANRLLV VLIKAKNLHS NQSKELLGKD VSVKVTLKHQ DLLQASSVEL EVLGQDDSGQ SCALGHCSLG LHTSGSERSH WEEMLKNPRR QIAMWHQLHL STEPVQPRAL LKFPDIYGPR PAVTAPEVIN NQAPKLHYCL DYDCQKAELF VTRLEAVTSN DRFSRHSVAG ELRLGLDGTS VPLGAAQWGE ARKLKKKQTK RAKHKINPVW NEMIMFELPD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice