HMGA2, Recombinant, Human, aa1-109, His-Tag (High Mobility Group AT-hook Protein 2, BABL, High Mobility Group Protein HMGI-C, HMGIC, LIPO, STQTL9)

Size

£607.00

SKU:: 137080
Molecular Weight:: 12.8
Purity:: ~80% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 50% glycerol, 2mM DTT.
Extra Details:: HMGA2 is a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Source: Recombinant protein corresponding to human HMGA2, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~12.8kD (117aa) AA Sequence: MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQEETEET SSQESAEEDL EHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.