CNBP, Recombinant, Human, aa1-170, His-Tag (Cellular Nucleic Acid-binding Protein, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9)

Size

£512.00

SKU:: 137026
Molecular Weight:: 21
Purity:: ≥90% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, 0.2M NaCl, 20% glycerol, 1mM DTT.
Extra Details:: CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. It functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Source: Recombinant protein corresponding to human CNBP, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~21kD (193aa) (MALDI-TOF) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSNECF KCGRSGHWAR ECPTGGGRGR GMRSRGRGFQ FVSSSLPDIC YRCGESGHLA KDCDLQEDAC YNCGRGGHIA KDCKEPKRER EQCCYNCGKP GHLARDCDHA DEQKCYSCGE FGHIQKDCTK VKCYRCGETG HVAINCSKTS EVNCYRCGES GHLARECTIE ATA Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.