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137005

BMP6, Recombinant, Human, aa375-513, His-Tag (Bone Morphogenetic Protein 6, VGR, VGR1)

Size

£607.00

SKU:
137005
Molecular Weight:
18
Purity:
~85% (SDS-PAGE)
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Supplied as a liquid in 10mM sodium-citrate buffer, pH 3.5, 10% glycerol.
Extra Details:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP6 has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. Source: Recombinant protein corresponding to human BMP6, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~18kD (164aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSASSR RRQQSRNRST QSQDVARVSS ASDYNSSELK TACRKHELYV SFQDLGWQDW IIAPKGYAAN YCDGECSFPL NAHMNATNHA IVQTLVHLMN PEYVPKPCCA PTKLNAISVL YFDDNSNVIL KKYRNMVVRA CGCH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice