BML-278, SIRT1 Inhibitor (N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine)

Size

£282.00

SKU:: 136761
Molecular Weight:: 391.5
Purity:: ~98% (TLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
Extra Details:: A structurally novel activator of SIRT1 (EC150=1uM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50uM respectively). Cell permeable. Solubility: DMSO (~5mg/ml) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.