136754
Apicidin, HDAC Inhibitor (Cyclo- N-O-methyl-L-tryptophanyl-Lisoleucinyl- Dpipecolinyl- L-2-amino-8-oxodecanoyl)
Size
£279.00
- SKU:
- 136754
- Molecular Weight:
- 623.8
- Purity:
- ~98% (TLC)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 183506-66-3
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
- Extra Details:
- Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50- 100nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Cell permeable. Solubility: DMSO (~10mg/ml) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice